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Sweet Syndrome in Pediatrics. A case report.
Jonathan Stevens G1, Jorge Yutronic H2, Javiera Pizarro O3
1Departamento Dermatología, Facultad de Medicina, Universidad de Chile, Chile.
Revista Chilena De Pediatria
|December 21, 2018
Summary
This case highlights pediatric Sweet Syndrome, a rare skin condition presenting with fever and painful plaques. Early recognition and treatment with corticosteroids led to rapid improvement in a young patient.
Area of Science:
- Dermatology
- Pediatrics
- Rheumatology
Background:
- Sweet's syndrome is a rare pediatric dermatosis of unknown cause.
- It is characterized by fever, neutrophilia, and painful skin plaques.
- Histologically, it involves dermal infiltration of neutrophils.
Observation:
- A 3-year-old female with complex chromosomopathy presented with fever and bullous skin lesions.
- Initial treatment for suspected impetigo was ineffective.
- Physical exam revealed erythematous-violaceous plaques and nodules with bullae.
Findings:
- Laboratory tests showed leukocytosis with marked neutrophilia and elevated CRP.
- Skin biopsy confirmed histopathological findings consistent with Sweet's Syndrome.
- Treatment with prednisone resulted in a significant clinical response.
Implications:
- Pediatric Sweet Syndrome requires a high index of suspicion when fever accompanies persistent skin lesions.
- While often idiopathic, associated conditions like proliferative disorders, infections, and immunodeficiencies should be screened for.
- Prompt diagnosis and corticosteroid treatment are crucial for managing pediatric Sweet Syndrome.
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