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Updated: Feb 10, 2026

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A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
Published on: March 8, 2022
2.9K
[Metastasis from a malignant melanoma presenting as a gall bladder polyp]
Helene Juul Würtz1, Sönke Detlefsen, Alan Patrick Ainsworth
1alan.ainsworth@dadlnet.dk.
Ugeskrift for Laeger
|May 30, 2018
Summary
Malignant melanoma can rarely metastasize to the gallbladder, presenting as a large polyp. Patients with large gallbladder polyps should be referred to specialized liver surgery centers for evaluation.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Gallbladder polyps exceeding 10 mm are associated with a higher risk of malignancy.
- Metastasis to the gallbladder is an uncommon presentation of distant cancer spread.
Observation:
- A 52-year-old woman presented with a large gallbladder polyp.
- This polyp was identified as a metastasis from a superficial spreading malignant melanoma.
Findings:
- The patient's malignant melanoma had been surgically resected eight years prior to this presentation.
- Common sites for malignant melanoma metastasis include soft tissue, lungs, liver, skin, and brain, with gallbladder metastasis being rare.
Implications:
- This case highlights the importance of considering rare metastatic sites in the differential diagnosis of large gallbladder polyps.
- Prompt referral of patients with large gallbladder polyps to specialized liver surgery centers is crucial for accurate diagnosis and management.
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