Related Experiment Video
Updated: Dec 11, 2025

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
Published on: August 5, 2021
Toward Sclera-Force-Based Robotic Assistance for Safe Micromanipulation in Vitreoretinal Surgery
Ankur Gupta1, Saurabh Singh1, Berk Gonenc1
1Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD 21218, USA.
Abstract:
In vitreoretinal surgery instruments are inserted through the sclera to perform precise surgical maneuvers inside the eyeball, which exceeds typical human capabilities. Robotic assistance can enhance the skills of a novice surgeon, provide guidance during tool manipulation based on the desired behavior defined by expert surgeons' maneuvers, and consequently improve the surgical outcome. This paper presents an experimental study characterizing the safe/desired magnitude of forces between the surgical instrument and the sclera insertion port as a function of the tool insertion depth. We explore two types of regressions, a polynomial and a sum of sines fit, to describe the observed user behavior during our one-user pilot study, based on which a variable admittance control scheme can be implemented to robotically guide other users towards this desired behavior for a safe operation.

