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Newborn Glaucoma: Do not Forget Infections.

Sushmita Kaushik1, Pankaj Kataria1, Gunjan Joshi1

  • 1Postgraduate Institute of Medical Education and Research.

Journal of Glaucoma
|May 31, 2018
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Summary
This summary is machine-generated.

Concurrent intrauterine rubella and cytomegalovirus (CMV) infections can cause severe congenital eye defects, including corneal opacification, glaucoma, and cataracts. Early diagnosis and multidisciplinary care are crucial for affected infants.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Teratology

Background:

  • Intrauterine infections are known to impact fetal eye development.
  • Rubella virus is associated with congenital cataracts, keratopathy, retinopathy, and glaucoma.
  • Cytomegalovirus (CMV) infection can cause chorioretinitis, optic nerve colobomas, and corneal opacities, but not typically cataracts or glaucoma.

Observation:

  • A case of concurrent intrauterine rubella and CMV infection is presented.
  • The infant presented with corneal opacification, severe congenital glaucoma, and congenital cataract.

Findings:

  • This is the first reported case of concurrent rubella and CMV infection.
  • The combined infections led to severe, complex ophthalmic manifestations in the newborn.

Implications:

  • Early identification of intrauterine infections is critical for infants with congenital eye anomalies.
  • Ocular findings like corneal opacification, glaucoma, and cataracts warrant investigation for infectious etiologies.
  • Management of such cases requires a multidisciplinary team approach due to complexity.