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A Case of Biliary Tract Infection Caused by KPC-2-Producing Kluyvera ascorbata

Lu Wang1,2, Ying Jing1, Kaisheng Lai1

  • 1Department of Microbiology, Chinese PLA General Hospital, Beijing, China.

Case Reports in Infectious Diseases
|June 1, 2018
PubMed

Insights

Carbapenemase-producing Kluyvera species, a rare cause of infection, were identified. This case highlights a KPC-2-producing Kluyvera ascorbata infection in a pediatric biliary tract infection.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Kluyvera species are known to cause infections, but carbapenemase production has not been previously documented.
  • Carbapenemase-producing Enterobacteriaceae (CPE) pose a significant global health threat due to limited treatment options.

Observation:

  • A 13-year-old female presented with a biliary tract infection.
  • The causative agent was identified as Kluyvera ascorbata.

Findings:

  • The isolated Kluyvera ascorbata strain was found to produce KPC-2 (Klebsiella pneumoniae carbapenemase 2), a significant carbapenemase.
  • This represents the first reported case of infection caused by carbapenemase-producing Kluyvera species.

Implications:

  • This finding expands the known spectrum of carbapenemase-producing organisms.
  • Clinicians should consider carbapenemase-producing Kluyvera in the differential diagnosis of infections, especially in patients with risk factors for antimicrobial resistance.
  • Further surveillance and characterization of carbapenemase-producing Kluyvera are warranted.

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