Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Principal Stresses in a Beam01:11

Principal Stresses in a Beam

755
In prismatic beams subject to arbitrary transverse loading, It is essential to analyze the interaction between shear forces and bending moments in order to understand stress distribution and ensure structural integrity. The highest normal or bending stress occurs at the outer fibers of the beam, decreasing linearly to zero at the neutral axis. In contrast, shear stress peaks at the neutral axis and diminishes toward the outer surfaces.
Analyzing principal stresses is crucial, especially in...
755
Real Time RT-PCR02:57

Real Time RT-PCR

65.3K
Real-time reverse transcription-polymerase chain reaction, or Real-time RT-PCR, is an analytical tool used to determine the expression level of target genes. The method involves converting mRNA to complementary DNA with the help of an enzyme known as reverse transcriptase, followed by the PCR amplification of the cDNA. These two processes can be performed simultaneously in a single tube or separately as a two-step reaction.
The real-time quantification of the number of amplified products is...
65.3K
Principal Moments of Area01:14

Principal Moments of Area

1.7K
In mechanics, the product of inertia and moments of inertia of area help to calculate the stability and performance of various structures and components. The coordinate transformation relations are used to calculate the moments and products of inertia for an area about the inclined axes. Further, the moments and products of inertia with respect to the principal axes can be determined using the moments and products of inertia about the inclined axes.
The principal moment of inertia axes are the...
1.7K
Principal Stresses01:24

Principal Stresses

858
The graphical depiction of normal and shearing stress equations is represented by a circle, demonstrating the interplay between these stresses under different angular conditions. The center of this circle C, located on the vertical axis, represents the average normal stress, while its radius shows the range of stress variations. At points A and B, where the circle intersects the horizontal axis, the maximum and minimum normal stresses are observed, occurring without shearing stress. These...
858
Principal Stresses: Problem Solving01:15

Principal Stresses: Problem Solving

596
When analyzing two planes intersecting at right angles under the influence of shearing, tensile, and compressive stresses, it is essential to identify principal planes, maximum shearing stress, and principal stresses. To find the principal planes, apply a formula that equates them to twice the shearing stress divided by the difference between tensile and compressive stresses.
596
Noncompartmental Analysis: Mean Residence Time01:05

Noncompartmental Analysis: Mean Residence Time

612
According to statistical moment theory, mean residence time (MRT) is an important measure in pharmacokinetics. MRT can be defined as the expected mean of a probability density function distribution. It provides valuable insights into drug disposition in the body.
After the administration of a drug through intravenous bolus injection, the drug molecules are distributed throughout the body and remain there for varying periods. The MRT represents the average time these drug molecules stay in the...
612

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Loss of NRF2 During Aging Contributes to Myocardial Functional Decline.

Antioxidants (Basel, Switzerland)·2026
Same author

Role of methanesulfonic acid in atmospheric particle nucleation and growth.

Nature·2026
Same author

Inhibition of a Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats 13 Activity by Peptidylarginine Deiminase IV Exacerbates Pancreatic Necrosis in Acute Pancreatitis.

Cellular and molecular gastroenterology and hepatology·2026
Same author

Deciphering the molecular landscape for the carotenoid-based coloration of leopard coral grouper (<i>Plectropomus leopardus</i>).

Marine life science & technology·2026
Same author

Three-year continuous maize cropping improves saline-alkali soil microenvironment and crop productivity.

Frontiers in microbiology·2026
Same author

Association between plasma ceramide levels and endothelial dysfunction in patients with acute coronary syndrome: A prospective observational study.

Medicine·2026
Same journal

Gaussian-modulated continuous-variable quantum key distribution over 60 km fiber using an integrated silicon photonic receiver.

Optics letters·2026
Same journal

E2E-OCT: end-to-end joint learning model using optical coherence tomography images for vocal cord leukoplakia diagnosis.

Optics letters·2026
Same journal

Holographic generation of panoramic 3D scenes by concave ellipsoidal mirror reflection.

Optics letters·2026
Same journal

Dual-pilot phase recovery with pair-wise maximum-ratio combining for coherent PONs.

Optics letters·2026
Same journal

Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

Optics letters·2026
Same journal

Quantitative estimation of deep-subwavelength scale via dark-field scattering axial energy concentration decay profiles.

Optics letters·2026
See all related articles

Related Experiment Video

Updated: Feb 9, 2026

Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies
07:12

Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies

Published on: November 19, 2020

2.6K

Real-time full-field optical angiography utilizing principal component analysis.

Mingyi Wang, Caizhong Guan, Wenjian Mao

    Optics Letters
    |June 2, 2018
    PubMed
    Summary
    This summary is machine-generated.

    We developed a real-time optical angiography method using principal component analysis (PCA) to visualize blood flow. This technique improves temporal resolution, enabling simultaneous monitoring of hemodynamic processes in vessels.

    More Related Videos

    Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models
    09:23

    Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models

    Published on: September 22, 2023

    3.7K
    Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons
    15:01

    Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons

    Published on: August 6, 2012

    14.1K

    Related Experiment Videos

    Last Updated: Feb 9, 2026

    Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies
    07:12

    Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies

    Published on: November 19, 2020

    2.6K
    Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models
    09:23

    Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models

    Published on: September 22, 2023

    3.7K
    Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons
    15:01

    Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons

    Published on: August 6, 2012

    14.1K

    Area of Science:

    • Biomedical Optics
    • Medical Imaging
    • Physiology

    Background:

    • Optical angiography is crucial for visualizing vascular networks.
    • Existing methods may face limitations in temporal resolution and signal separation.
    • Real-time monitoring of hemodynamics is essential for diagnosing vascular conditions.

    Purpose of the Study:

    • To develop a real-time full-field optical angiography method.
    • To utilize principal component analysis (PCA) for enhanced blood flow signal extraction.
    • To validate the method's efficacy in phantom and in-vivo experiments.

    Main Methods:

    • An undersampled laser Doppler method was employed to acquire raw image data.
    • Principal component analysis (PCA) was used to differentiate dynamic blood flow signals from static background.
    • Phantom experiments were conducted to optimize frame number for image reconstruction.

    Main Results:

    • PCA effectively separated blood flow signals from static background components.
    • The method achieved high temporal resolution, allowing for efficient blood flow extraction from finite raw images.
    • Phantom experiments confirmed the optimal frame number for angiographic image reconstruction.
    • In-vivo testing on a rabbit ear demonstrated successful monitoring of global and simultaneous hemodynamic processes.

    Conclusions:

    • The developed real-time optical angiography method with PCA offers improved temporal resolution.
    • This technique enables effective visualization and monitoring of vascular hemodynamics.
    • The findings support the potential of this method for clinical applications in vascular imaging.