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Quality Assurance01:19

Quality Assurance

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Quality assurance is the overarching term used to describe the activities employed to ensure the proper performance of a system. These activities can be classified into three categories: quality control, quality assessment, and internal corrective measures. Typically, these activities work cyclically: quality control is performed before and during the analysis, while quality assessment occurs during and after the investigation. Internal corrective measures are implemented based on the findings...
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Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
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In concrete preparation, the quality of water is paramount as it affects the strength and durability of the concrete. Potable water is usually preferred; however, it must not have excessive sodium or potassium to prevent compromising the concrete's integrity. Water quality is typically evaluated based on impurities such as dissolved solids, chlorides, and sulfates, and its pH value is ideally between 6 and 8. Even slightly acidic natural water may be acceptable unless it contains harmful...
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Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
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When the quality of water for concrete preparation is uncertain, its impact on the setting time of cement and compressive strength of mortar is assessed by comparison with de-ionized or distilled water benchmarks. American Society for Testing and Materials (ASTM) C1602 requires the setting times to be within 90 minutes of the control, British Standard (BS) 3146:1980 allows a 30-minute variance in the initial setting, while British Standards European Norm (BS EN) 1008 specifies initial setting...
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Nursing Clinical Information System (NCIS)
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A quality assurance program for clinical PDT.

Andreea Dimofte1, Jarod Finlay1, Yi Hong Ong1

  • 1Departments of Radiation Oncology, University of Pennsylvania, Philadelphia, PA.

Proceedings of Spie--The International Society for Optical Engineering
|June 5, 2018
PubMed
Summary
This summary is machine-generated.

Accurate light dosimetry is crucial for successful photodynamic therapy (PDT). This study details a quality assurance program ensuring precise light dose measurements through detector calibration and power meter intercomparison, achieving high accuracy.

Keywords:
LEDLight doseQAcalibrationphotodynamic therapy

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Area of Science:

  • Medical Physics
  • Biomedical Engineering

Background:

  • Photodynamic therapy (PDT) outcomes rely on precise light dose delivery.
  • Quality assurance (QA) is essential for accurate light dosimetry in PDT.

Purpose of the Study:

  • To establish a comprehensive QA program for PDT light dosimetry.
  • To evaluate the long-term calibration uncertainty of detectors and consistency of measurement devices.

Main Methods:

  • Calibration of isotropic detectors using a calibrated LED light source in an integrating sphere.
  • Intercomparison of power meters to assess laser power and light fluence rate consistency.
  • Examination of LED light source stability and spectrometer calibration.

Main Results:

  • The internal LED calibration method achieved an accuracy of ±4%.
  • Power meter intercomparison demonstrated long-term consistency within 3% for power and fluence rate.
  • The QA program ensures reliable measurements for PDT dose calculations.

Conclusions:

  • A robust QA program is vital for accurate light dosimetry in PDT.
  • The established methods provide reliable calibration and intercomparison for critical PDT measurement devices.
  • This ensures consistent and safe delivery of light doses in clinical applications.