Posttraumatic Stress Disorder Symptom Association With Subsequent Risky and Problem Drinking Initiation

Kara M Bensley1, Amber D Seelig, Richard F Armenta

  • 1Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA (KMB, ADS, AJL, CCM, EJB); Henry M Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (RFA, ACR, IGJ); Department of Epidemiology, University of Washington School of Public Health, Seattle, WA (AJL, EJB); Department of Health Services, University of Washington School of Public Health, Seattle, WA (KMB, CCM, ECW); Seattle-Denver Center of Innovation for Veteran-Centered and Value-Driven Care, Health Services Research and Development, Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA (KMB, AJL, CCM, ECW); Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (AVP, JBB); Military Population Health Directorate, Naval Health Research Center, San Diego, CA (RPR); Department of Biostatistics, University of Washington School of Public Health, Seattle, WA (AVP); Department of Psychology, University of Washington, Seattle, WA (JBB); Department of Kinesiology, College of Education, Health and Human Services, California State University, San Marcos (RFA).

Summary

Specific posttraumatic stress disorder (PTSD) symptoms, like irritability, are linked to starting unhealthy alcohol use. Emotional numbing and dysphoric arousal symptom clusters also predict problem drinking, highlighting key targets for intervention.

Related Concept Videos

Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
569
Initiation of Translation02:33

Initiation of Translation

Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
39.1K
Initiation of Translation02:33

Initiation of Translation

8.1K
Transcription Initiation01:47

Transcription Initiation

Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
The promoters and enhancers and their accessory proteins allow tight regulation of...
21.2K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.4K
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
604