Related Experiment Video
Updated: Feb 9, 2026

Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
[Airway inflammation in sleep disordered breathing children: preliminary results]
Abstract:
Objective:To assess the clinical significance of nasal nitric oxide(NNO) levels in children with sleep disordered breathing(SDB).Method:Thirty children with SDB and twenty healthy children were enrolled. The NNO levels were measured non-invasively using a NIOX MINO system. SPSS statistics 20.0 software was used to analyze the data. Result:Compared to healthy children,NNO level was significant higher in children with SDB(Z=-2.215,P<0.05) .Correlation analysis showed that SDB children's NNO level was directly correlated with AHI(r=0.429,P<0.05),and it was inversely correlated with nadir SaO2(r=-0.482,P<0.01).But NNO level was not significantly correlated with other polysomnographic parameters. Conclusion:Our data suggested that NNO levels might be useful for evaluating the disease severity in SDB children.
Related Concept Videos
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
REM Sleep Behavior Disorder
RBD is significantly associated with...
Breathing
Inflammation
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Stages of Sleep
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...

