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Author Spotlight: Development of an Enhanced Protocol for Rapid and Accurate Isolation of Campylobacter from Food Products
Published on: February 23, 2024
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Investigating the Association Between the Caecal Microbiomes of Broilers and Campylobacter Burden
Ioannis Sakaridis1, Richard J Ellis2, Shaun A Cawthraw2
1School of Veterinary Medicine, University of Surrey, Guildford, United Kingdom.
Frontiers in Microbiology
|June 7, 2018
Summary
Reducing high levels of the foodborne pathogen Campylobacter in chickens may be possible by modulating the gut microbiome. High Campylobacter loads were associated with increased Enterobacteriaceae and decreased Lactobacillus in chicken ceca.
Area of Science:
- Microbiology
- Food Safety
- Animal Science
Background:
- Campylobacter is a major foodborne bacterial pathogen transmitted through undercooked poultry.
- High densities of Campylobacter in broiler ceca are common, posing a food safety risk.
- Understanding Campylobacter colonization dynamics and microbiome interactions is crucial for reducing food poisoning.
Purpose of the Study:
- To characterize the caecal microbiome of Campylobacter-colonized broilers.
- To investigate the relationship between Campylobacter loads and specific bacterial groups in the chicken gut.
- To identify potential microbial targets for reducing Campylobacter in poultry.
Main Methods:
- Analysis of caecal samples from 100 randomly selected broilers across four farms.
- Amplified 16S rRNA gene sequencing for bacterial taxonomic analysis.
- Correlation analysis between Campylobacter counts and bacterial group abundance.
Main Results:
- Bacteroidetes and Firmicutes were the dominant bacterial phyla across all samples.
- No clear link was found between Campylobacter and Firmicutes, Bacteroidetes, or Tenericutes levels.
- High Campylobacter loads (>9 log CFU g⁻¹) were associated with increased Enterobacteriaceae and decreased Lactobacillus abundance.
Conclusions:
- The chicken caecal microbiome composition varies significantly between farms.
- Specific bacterial groups, Enterobacteriaceae and Lactobacillus, show altered abundance correlating with high Campylobacter loads.
- Modulating the chicken microbiota, particularly targeting Lactobacillus and Enterobacteriaceae, may offer a strategy to reduce Campylobacter for improved food safety.
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