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Encapsulated L-Lysine: from physicochemical properties to broiler responses
Hosna Hajati1, Amirhossein Alizadeh Ghamsari1, Seyyed Abdollah Hosseini1
1Department of Animal and Poultry Nutrition and Physiology, Animal Science Research Institute of Iran, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Veterinary and Animal Science
|August 15, 2026
Summary
Micro-encapsulated L-lysine improved feed efficiency in broiler chickens during early growth. This innovative feed additive can partially replace conventional lysine sources without impacting carcass traits, supporting precision nutrition goals.
Area of Science:
- Animal Science
- Nutritional Biochemistry
- Poultry Science
Background:
- Optimizing amino acid bioavailability is crucial for broiler production efficiency and environmental sustainability.
- Minimizing nitrogen excretion through precise nutrient formulation is a key goal in modern animal agriculture.
Purpose of the Study:
- To evaluate the impact of dietary micro-encapsulated L-lysine on broiler growth, feed efficiency, carcass yield, and blood parameters.
- To assess the potential of micro-encapsulated L-lysine as a partial replacement for conventional L-lysine HCl in broiler diets.
Main Methods:
- Characterization of micro-encapsulated L-lysine physicochemical properties using FTIR, DSC, and FESEM.
- A feeding trial with 600 broiler chicks across six dietary treatments, including a control and varying levels of micro-encapsulated L-lysine (60-100%).
- Analysis of growth performance (body weight, feed intake), feed conversion ratio (FCR), carcass traits, and serum metabolites (HDL-cholesterol, globulin).
Main Results:
- Micro-encapsulated L-lysine did not significantly affect final body weight or feed intake.
- A significantly lower feed conversion ratio was observed in broilers fed diets with 80-100% micro-encapsulated L-lysine during the starter phase (1-28 days).
- Dietary inclusion of 70-80% micro-encapsulated L-lysine increased HDL-cholesterol and decreased serum globulin levels compared to the control.
Conclusions:
- Micro-encapsulated L-lysine shows potential for enhancing feed efficiency in broiler chickens during early developmental stages.
- Partial replacement of crystalline L-lysine with micro-encapsulated L-lysine is feasible in broiler diets without adverse effects on carcass characteristics.
- This approach supports precision nutrition strategies by optimizing amino acid delivery and potentially reducing nitrogen excretion.

