Biomacromolecules as carriers in drug delivery and tissue engineering

Yujie Zhang1, Tao Sun1, Chen Jiang1

  • 1Key Laboratory of Smart Drug Delivery, Ministry of Education, State Key Laboratory of Medical Neurobiology, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai 200032, China.

Keywords:
ABD, albumin binding domainACM, aclacinomycinACS, absorbable collagen spongeADH, adipic dihydrazideART, artemisininASF, Antheraea mylitta silk fibroinATRA, all-trans retinoic acidATS, artesunateBCEC, brain capillary endothelial cellsBMP-2, bone morphogenetic protein-2BSA, bovine serum albuminBSF, Bombyx mori silk fibroinBiomacromoleculeCC-HAM, core-crosslinked polymeric micelle based hyaluronic acidCD, cyclodextrinCD-NPs, amphiphilic MMA–tBA β-CD star copolymers that are capable of forming nanoparticlesCD-g-CS, chitosan grafted with β-cyclodextrinCD/BP, cyclodextrin–bisphosphonate complexesCIA, collagen-induced arthritisCM, collagen matricesCMD-ChNP, carboxylmethyl dextran chitosan nanoparticleDHA, dihydroartesunateDOXO-EMCH, (6-maleimidocaproyl)hydrazone derivative of doxorubicinDOX–TRF, doxorubincin–transferrin conjugateDTX-HPLGA, HA coated PLGA nanoparticulate docetaxelDrug deliveryECM, extracellular matrixEMT, epithelial mesenchymal transitionEPR, enhanced permeability and retentionFcRn, neonatal Fc receptorGAG, glycosaminoglycanGC-DOX, glycol–chitosan–doxorubicin conjugateGDNF, glial-derived neurotrophic factorGO, grapheme oxideGSH, glutathioneGd, gadoliniumHA, hyaluronic acidHA-CA, catechol-modified hyaluronic acidHCF, heparin-conjugated fibrinHDL, high density lipoproteinHEK, human embryonic kidneyHSA, human serum albuminIDL, intermediate density lipoproteinINF, interferonLDL, low density lipoproteinLDLR, low density lipoprotein receptorLDV, leucine–aspartic acid–valineLMWH, low molecular weight heparinMSA, mouse serum albuminMTX–HSA, methotrexate–albumin conjugateNIR, near-infraredNSCLC, non-small cell lung cancerOP-Gel-NS, oxidized pectin-gelatin-nanosliverPEC, polyelectrolytePTX, paclitaxelPolysaccharideProteinRES, reticuloendothelial systemRGD, Arg–Gly–Asp peptideSF, silk fibroinSF-CSNP, silk fibroin modified chitosan nanoparticleSFNP, silk fibroin nanoparticleSPARC, secreted protein acidic and rich in cysteineTRAIL, tumor-necrosis factor-related apoptosis-inducing ligandTf, transferrinTfR, transferrin receptorTissue engineeringVEGF, vascular endothelial growth factorVLDL, very low density lipoproteinpDNA, plasmid DNArHDL, recombinant HDLrhEGF-2/HA, recombinant human fibroblast growth factor type 2 in a hyaluronic acid carrier

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