[Two-step strategy for the treatment of complex coronary artery disease and aortic stenosis in a patient with

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Paolo A Pagnotta1, Mauro Chiarito1, Elton Pllaha1

  • 1Dipartimento Cardiovascolare, Humanitas Research Hospital, Rozzano (MI).

Giornale Italiano Di Cardiologia (2006)
|June 7, 2018
PubMed

Insights

Coronary artery disease and aortic stenosis often occur together, sharing similar causes like atherosclerosis. Management is shifting from surgery to less invasive percutaneous procedures like transcatheter aortic valve implantation.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology

Background:

  • Coronary artery disease (CAD) and aortic stenosis (AS) are common cardiovascular conditions.
  • Both CAD and AS share similar pathophysiological mechanisms, primarily driven by atherosclerosis.
  • Risk factors for AS overlap significantly with those for CAD.

Observation:

  • Atherosclerosis is the central pathological feature in both coronary artery disease and aortic stenosis.
  • Established risk factors for developing aortic stenosis are also prevalent in patients with coronary artery disease.

Findings:

  • Historically, surgical interventions like coronary artery bypass grafting (CABG) and surgical aortic valve replacement (SAVR) were the standard treatments.
  • The advent of transcatheter aortic valve implantation (TAVI) offers a less invasive alternative.

Implications:

  • The management paradigm for patients with coexisting CAD and AS is evolving.
  • A percutaneous approach, including TAVI, is increasingly likely to become the preferred strategy, potentially improving patient outcomes and reducing invasiveness.

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