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Chemical Speciation and Metallomics.

Jemmyson Romário de Jesus1,2,3, Luana Ferreira da Costa1,2,3, Eraldo Luiz Lehmann1,2,3

  • 1Universidade Estadual de Campinas - Unicamp, Campinas, São Paulo, Brazil.

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Summary

Chemical speciation is crucial for metallomics studies, analyzing metals and organic structures. This chapter explores its applications in human health, food, drugs, forensics, nanoscience, and geology, highlighting advancements and sample preparation techniques.

Keywords:
DrugsFoodForensicGeochemistryHealthyNanoscienceNutrition

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Area of Science:

  • Metallomics
  • Analytical Chemistry

Background:

  • Chemical speciation is fundamental to metallomics, requiring evaluation of metals/metalloids and organic structures.
  • Understanding the interplay between metal ions and biomolecules is essential for various scientific disciplines.

Purpose of the Study:

  • To review the diverse applications of chemical speciation within metallomics.
  • To highlight advancements in chemical speciation techniques relevant to metallomics.
  • To discuss critical aspects of sample preparation and data integrity in metallomics.

Main Methods:

  • Review of existing literature on chemical speciation techniques.
  • Analysis of case studies across various metallomics fields.
  • Discussion of methodological challenges and solutions in sample handling.

Main Results:

  • Chemical speciation finds broad application in human health risk assessment, food analysis, pharmaceuticals, forensic science, nanoscience, and geological studies.
  • Significant advancements have been made in speciation analysis, improving accuracy and sensitivity.
  • Effective sample preparation and preservation strategies are vital for reliable metallomics data.

Conclusions:

  • Chemical speciation is an indispensable tool for comprehensive metallomics research.
  • Continued development of speciation methods will further enhance our understanding of metal behavior in biological and environmental systems.
  • Standardized protocols for sample preparation are crucial for interdisciplinary metallomics studies.