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Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation

Yan-Yun Liu1,2, Gregory A Brent3,4

  • 1Department of Medicine, David Geffen School of Medicine at UCLA and VA Greater Los Angles Healthcare System, Los Angeles, CA, USA. yyl@ucla.edu.

Methods in Molecular Biology (Clifton, N.J.)
|June 13, 2018
PubMed
Summary

Thyroid hormone receptors (TRs) are modified by sumoylation, impacting gene expression. This study details methods to investigate TR sumoylation, crucial for understanding thyroid hormone signaling.

Keywords:
In vitro sumoylationIn vivo (cells) sumoylationIn vivo (tissue) sumoylationPhosphorylationThyroid hormone receptor (TR)

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