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A systematic analysis on possibility of water fluoridation causing hypothyroidism
Nallan C S K Chaitanya1, P Karunakar2, Neeharika Satya Jyothi Allam1
1Department of Oral Medicine and Radiology, Principal, Panineeya Institute of Dental Sciences, Hyderabad, Telangana, India.
Summary
Excessive fluoride intake is linked to hypothyroidism. This systematic review highlights a correlation, emphasizing the need for more research on this emerging health concern.
Area of Science:
- Environmental Health
- Endocrinology
- Public Health
Background:
- Community water fluoridation is a recognized preventive dental care strategy.
- Excessive fluoride intake is associated with skeletal and dental fluorosis.
- Limited literature exists on the extraskeletal effects of fluoride, particularly on thyroid function.
Purpose of the Study:
- To systematically review controlled studies investigating the relationship between fluoride exposure and thyroid function.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (PubMed, MEDLINE, EMBASE, Cochrane Library, EBSCO) for studies published between 1981 and 2015.
- Keywords included "fluoride and hypothyroidism," "dental fluorosis and thyroid disorders," and "excessive water fluoridation and hypothyroidism."
- Ten full-text articles meeting inclusion criteria were analyzed.
Main Results:
- Analysis of 10 selected studies indicated a positive correlation between elevated fluoride levels and hypothyroidism.
- The findings suggest a potential link between excessive fluoride exposure and impaired thyroid function.
Conclusions:
- A positive correlation exists between excess fluoride and hypothyroidism.
- Further well-controlled research is warranted to understand this emerging public health issue.
- Community awareness and health informatics networks are crucial for addressing this concern.
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