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Updated: Feb 9, 2026

Single-Molecule Imaging of Nuclear Transport
Published on: June 9, 2010
Nuclear Medicine Imaging in the Dentomaxillofacial Region
Heidi R Wassef1, Patrick M Colletti2
1Department of Radiology, Keck School of Medicine of USC, PET Center, 1500 San Pablo Street, Los Angeles, CA 90033, USA.
Abstract:
Nuclear medicine studies evaluate physiology on a molecular level providing earlier detection of lesions before morphologic change is evident. 99mTc-MDP and 18F-fluoride bone scans detect osteomyelitis earlier than radiographs and computed tomography (CT); aid in diagnosis of temporomandibular joint disorder; and evaluate activity of condylar hyperplasia, extent of Paget disease, and viability of bone grafts. 18F-FDG PET/CT distinguish between soft tissue and bone infections and diagnose osteomyelitis complicated by fracture or surgery. FDG PET is more accurate than CT alone and has a major role in staging, restaging, and assessing response to therapy for head and neck malignancies and in detecting sequelae of therapy.
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