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[MODERN ASPECTS OF DIAGNOSIS AND TREATMENT OF HEART FAILURE, AS A MANIFESTATION OF ANTHRACYCLINE CARDIOTOXICITY
Kh Saganelidze1, N Kavtaradze1
1Niu-Vigen University, Tbilisi, Georgia.
Georgian Medical News
|June 16, 2018
Summary
Anthracycline chemotherapy drugs can cause cardiotoxicity, leading to heart failure. Early diagnosis and multidisciplinary management are crucial for patients undergoing cancer treatment.
Area of Science:
- Cardiology
- Oncology
- Pharmacology
Background:
- Cardiotoxicity from anthracyclines is a significant concern in cancer therapy.
- Anthracyclines are potent chemotherapy agents known for their cardiotoxic effects.
- Cardiotoxicity can manifest early or late, even with concomitant diseases.
Purpose of the Study:
- To review the cardiotoxicity of anthracyclines in cancer patients.
- To examine the diagnosis, treatment, and prevention of anthracycline-induced cardiotoxicity.
- To highlight the management of heart failure secondary to anthracycline treatment.
Main Methods:
- Literature review of cardiotoxicity associated with anthracycline chemotherapy.
- Analysis of cardiovascular complications during chemotherapeutic treatment.
- Examination of diagnostic and therapeutic recommendations from European societies (ESMO, ESC).
Main Results:
- Identified 9 main categories of cardiovascular complications.
- Detailed review of heart failure as a manifestation of cardiotoxicity.
- Discussed early diagnosis and management strategies for cardiac insufficiency.
- Reviewed treatment and diagnosis in patients with concomitant diseases.
Conclusions:
- Multidisciplinary team management is essential for patients receiving anthracyclines.
- Early detection and intervention are key to managing anthracycline cardiotoxicity.
- Adherence to guidelines from ESMO and ESC is recommended for optimal patient care.
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