Related Experiment Video
Updated: Feb 8, 2026

Noninvasive Intratracheal Lipopolysaccharide Instillation in Mice
Published on: March 31, 2023
Noninvasive Options
Giuseppe Bello1, Alessandra Ionescu Maddalena1, Valentina Giammatteo1
1Department of Anesthesia and Intensive Care, Fondazione Policlinico Universitario Agostino Gemelli, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy.
Abstract:
Noninvasive ventilation (NIV) has assumed a central role in the treatment of selected patients with acute respiratory failure due to exacerbated chronic obstructive pulmonary disease or acute cardiogenic pulmonary edema. Recent advances in the understanding of physiologic aspects of NIV application through different interfaces and ventilator settings have led to improved patient-machine interaction, enhancing favorable NIV outcome. In recent years, the growing role of NIV in the acute care setting has led to the development of technical innovations to overcome the problems related to gas leakage and dead space, improving the quality of the devices and optimizing ventilation modes.
Related Concept Videos
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Probability Laws
Bystander Effect
Naturalistic Observations

