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Updated: Feb 8, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
Published on: June 1, 2012
Electrochemical sensing of attomolar miRNA combining cascade strand displacement polymerization and
Peng Miao1, Yiting Jiang, Tian Zhang
1Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, P. R. China. miaopeng@sibet.ac.cn.
Abstract:
Herein, we have developed a distinctive electrochemical sensing platform for miRNA assay. Target miRNA initiates two cycles of polymerization, nicking, and displacement reactions, which lead to the variation of the distance between redox molecules and the electrode surface. In addition, a reductant is employed for further electrochemical amplification.
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