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Diagnostic challenges and future perspectives in fracture-related infection

Mario Morgenstern1, Richard Kühl2, Henrik Eckardt1

  • 1Department of Orthopedic Surgery and Traumatology, University Hospital Basel, Switzerland.

Injury
|June 23, 2018
PubMed

Insights

Fracture-related infection (FRI) diagnosis is challenging in orthopaedic trauma. A new interdisciplinary algorithm, based on a recent definition, aids in standardizing diagnosis when universal tests are unavailable.

Area of Science:

  • Orthopaedic trauma surgery
  • Infectious disease diagnostics

Background:

  • Fracture-related infection (FRI) presents significant challenges in orthopaedic trauma.
  • FRI has severe patient consequences and socio-economic impact.
  • Current diagnostic criteria for FRI are not standardized.

Purpose of the Study:

  • To present current diagnostic modalities for FRI.
  • To introduce an interdisciplinary diagnostic algorithm for FRI based on a recent definition.
  • To discuss future diagnostic techniques for FRI.

Main Methods:

  • Review of current diagnostic modalities for fracture-related infection.
  • Presentation of an interdisciplinary diagnostic algorithm.
  • Discussion of emerging diagnostic technologies.

Main Results:

  • Fracture-related infection requires an interdisciplinary approach.
  • A recently proposed definition for FRI is available.
  • A standardized diagnostic algorithm is crucial due to the lack of a universal diagnostic test.

Conclusions:

  • Standardized diagnostic algorithms are mandatory for accurate FRI diagnosis.
  • An interdisciplinary approach is essential for managing FRI.
  • Future diagnostic techniques hold promise for improved FRI detection.
Keywords:
DiagnosisFracture-related infectionHistologyImaging modalitiesMicrobiology

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