Related Experiment Video
Updated: Feb 8, 2026

Viral Nanoparticles for In vivo Tumor Imaging
Published on: November 16, 2012
Nanoparticle transport pathways into tumors
S M Moghimi1,2,3, D Simberg3
11School of Pharmacy, The Faculty of Medical Sciences, Newcastle University, King George VI Building, Newcastle upon Tyne, NE1 7RU UK.
Abstract:
Two transport pathways (interendothelial and transendothelial routes) have long been proposed for entry of nanoparticles from the blood circulation into solid tumors. We examine and discuss available evidence supporting interendothelial and transendothelial transport processes and suggest new avenues for re-evaluating these pathways. Understanding of integrative mechanisms controlling nanoparticle extravasation into tumors is important for improving engineering and performance of anti-cancer nanopharmaceuticals.
Related Concept Videos
C4 Pathway and CAM
C4 Pathway
The C4 pathway is used by plants such as...
Short-distance Transport of Resources
Facilitated Transport
Primary Active Transport
Secondary Active Transport
Regulated mRNA Transport

