Related Experiment Video
Updated: Feb 8, 2026

Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration
Published on: March 18, 2016
Spontaneous transformation of a concealed to manifest posteroseptal accessory pathway requiring epicardial ablation
Adam Lee1,2, James Lindemann3, Oscar Davison1
1Department of Cardiology The Prince Charles Hospital Brisbane QLD Australia.
Abstract:
Concealed accessory pathways (APs) are considered benign as they can only sustain orthodromic atrioventricular re-entrant tachycardia (ORT). We describe a unique case of a concealed posteroseptal AP where longitudinal surveillance following repeated failed ablation attempts due to abnormal coronary sinus (CS) anatomy revealed spontaneous development of manifest pre-excitation. The pathway was ultimately ablated via the percutaneous epicardial approach. The potential for development of Wolff-Parkinson-White (WPW) syndrome in patients with concealed APs has implications for ongoing surveillance in these patients.
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