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Updated: Feb 8, 2026
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Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
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[Alpha-Gal-associated delayed red meat anaphylaxis as an occupational disease]
W Anemüller1, M Mohr1, R Brans2
1Klinik für Dermatologie, Allergologie und Venerologie, Universität zu Lübeck, Lübeck, Deutschland.
Summary
A chef developed delayed anaphylaxis due to alpha-Gal allergy from red meat. This underdiagnosed, potentially fatal condition was recognized as an occupational disease.
Area of Science:
- Allergy and Immunology
- Occupational Health
Background:
- Delayed angioedema can be a symptom of alpha-Gal syndrome.
- Alpha-Gal syndrome is an allergic reaction to red meat.
Observation:
- A 30-year-old chef experienced recurrent delayed angioedema.
- IgE antibodies against galactose-alpha-(1,3)-galactose (alpha-Gal) were detected, identifying alpha-Gal as the cause.
Findings:
- The patient was diagnosed with delayed anaphylaxis due to alpha-Gal.
- The allergy was linked to his profession, leading to its classification as an occupational disease.
Implications:
- This case highlights alpha-Gal allergy as an underdiagnosed, potentially life-threatening occupational disease.
- Increased awareness is crucial for timely diagnosis and management of alpha-Gal syndrome in at-risk professions.
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