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Updated: Feb 8, 2026

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Fabrication of Tongue Extracellular Matrix and Reconstitution of Tongue Squamous Cell Carcinoma In Vitro
Published on: June 20, 2018
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Rare glomangiosarcoma of the tongue
Sumetha Rajendran1, Arthur Harry Henderson2, Stuart Gillett2
1Oral and Maxillofacial Surgery, University of Bristol Medical School, Bristol, UK.
BMJ Case Reports
|July 6, 2018
Summary
This study reports the first intraoral malignant glomus tumour (glomangiosarcoma) found on the dorsal tongue. Surgical excision was performed, but malignant features necessitated re-excision.
Area of Science:
- Oral pathology
- Surgical oncology
- Neoplasms
Background:
- Glomus tumours are rare neoplasms originating from the glomus apparatus.
- Subungual locations are most common, with rare occurrences on the dorsal tongue.
Observation:
- A case of a glomus tumour on the posterior dorsal tongue of a middle-aged man is presented.
- The tumour was surgically excised.
- Immunohistological analysis confirmed glomus tumour features.
Findings:
- This represents the first reported intraoral malignant glomus tumour (glomangiosarcoma) in English literature.
- Malignant features were identified alongside typical glomus tumour characteristics.
- Re-excision was recommended due to the discovered malignancy.
Implications:
- Highlights the potential for malignancy in intraoral glomus tumours.
- Emphasizes the importance of thorough histopathological examination for accurate diagnosis.
- Suggests the need for careful surgical planning and potential re-excision in such rare cases.
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