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Updated: Feb 8, 2026

A Simple Cell-based Immunofluorescence Assay to Detect Autoantibody Against the N-Methyl-D-Aspartate NMDA Receptor in Blood
Published on: January 9, 2018
Teratoma-negative anti-NMDA receptor encephalitis presenting with a single generalized tonic-clonic seizure
Andy Cheuk-Him Ng1, Miljan Tripic2, Seyed M Mirsattari2,3,4,5
1Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Abstract:
Herein, we describe a case report of anti-NMDA receptor encephalitis characterized by a single generalized tonic-clonic seizure and predominantly psychiatric symptoms, persisting long after EEG abnormalities had resolved. We discuss common presentations of anti-NMDA receptor encephalitis and advocate for the inclusion of this disease entity in the differential diagnosis of patients presenting with one generalized tonic-clonic seizure and prominent psychiatric symptoms.
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