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Depth-resolved mapping of muscular bundles in myocardium pulmonary junction using optical coherence tomography

Zhifang Li1, Qinggong Tang2, Timm Dickfeld3

  • 1Fujian Normal Univ., China.

Journal of Biomedical Optics
|July 8, 2018
PubMed

Insights

Optical coherence tomography (OCT) visualizes myocardial extensions causing atrial fibrillation (AF). This imaging technique can guide catheter ablation procedures for AF treatment.

Area of Science:

  • Cardiovascular Medicine
  • Medical Imaging
  • Cardiac Electrophysiology

Background:

  • Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with significant patient morbidity.
  • Myocardial extensions from the atrium into the pulmonary veins are identified as a primary cause of AF-initiating triggers.

Purpose of the Study:

  • To investigate the utility of Optical Coherence Tomography (OCT) for visualizing myocardial extensions at the pulmonary vein-cardiac muscle junction.
  • To assess OCT's potential in guiding catheter radio-frequency ablation for AF treatment.

Main Methods:

  • Application of OCT for direct visualization of myocardial extensions in the myocardium-pulmonary junction.
  • Acquisition and analysis of imaging data from two perspectives: cross-sectional and en face.

Main Results:

  • Cross-sectional OCT images effectively located the myocardium-pulmonary junction.
  • En face OCT images provided depth-resolved information on the arrangement of muscular bundles within the myocardium-pulmonary junction.

Conclusions:

  • OCT imaging offers a viable method for visualizing myocardial extensions implicated in AF.
  • OCT demonstrates potential as a tool to guide catheter radio-frequency ablation procedures for AF treatment.

Keywords:
muscular bundleoptical coherence tomographyradius

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