Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

3.5K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.5K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

3.4K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.4K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.2K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.2K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.4K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.4K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.4K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.4K
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

3.9K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Update on environmental determinants of allergic diseases.

The Journal of allergy and clinical immunology·2026
Same author

CBX7 functions as a methylation-dependent inducer of gene transcription and regulator of cytosolic signaling in lymphoid cells.

Science advances·2026
Same author

Allergens abrogate antiinflammatory DNA effects and unmask macrophage-driven neutrophilic asthma via ILC2/STING/TNF-α signaling.

The Journal of clinical investigation·2025
Same author

Update on type 2 immunity.

The Journal of allergy and clinical immunology·2024
Same author

Modeling Asthma in Mice Using Common Aeroallergens.

Methods in molecular biology (Clifton, N.J.)·2022
Same author

The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma.

The Journal of experimental medicine·2021

Related Experiment Video

Updated: Feb 8, 2026

Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

6.6K

Mouse Models of Asthma.

Magdalena M Gorska1,2

  • 1Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health, Denver, CO, USA. gorskam@njhealth.org.

Methods in Molecular Biology (Clifton, N.J.)
|July 11, 2018
PubMed
Summary

Mouse models are essential for understanding asthma development and testing new therapies. This chapter details four distinct models and surgical methods for evaluating experimental asthma.

Keywords:
AllergenBronchoalveolar lavageExperimental asthmaImmunizationLungMouse model

More Related Videos

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.3K
Asthma Detection Research Based on Voice Signal Processing and Machine Learning
04:04

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

1.0K

Related Experiment Videos

Last Updated: Feb 8, 2026

Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

6.6K
Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.3K
Asthma Detection Research Based on Voice Signal Processing and Machine Learning
04:04

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

1.0K

Area of Science:

  • * Pulmonology and immunology research.
  • * Animal models in disease research.

Background:

  • * Asthma pathogenesis requires detailed mechanistic understanding.
  • * Development of novel therapeutic strategies is ongoing.
  • * Validated experimental models are crucial for preclinical research.

Purpose of the Study:

  • * To describe four distinct mouse models for asthma research.
  • * To highlight the unique advantages of each model.
  • * To outline essential surgical techniques for asthma assessment.

Main Methods:

  • * Description of four established mouse models of asthma.
  • * Detailed explanation of surgical procedures for experimental asthma assessment.
  • * Focus on models enabling specific research questions.

Main Results:

  • * Provides a comprehensive overview of available asthma models.
  • * Offers practical guidance on model selection.
  • * Details critical surgical techniques for data acquisition.

Conclusions:

  • * Selection of appropriate mouse models is key to advancing asthma research.
  • * Surgical techniques are vital for accurate assessment of asthma.
  • * These models facilitate the study of asthma mechanisms and treatment efficacy.