Septic Shock and Multiple Organ Failure After Office Endometrial Sampling

Area of Science:

• Gynecology
• Infectious Diseases
• Patient Safety

Background:

• Office endometrial biopsy with a Pipelle cannula is a standard, safe, and cost-effective procedure for endometrial sampling.
• This method is accurate for diagnosing endometrial conditions, including endometrial carcinoma, with minimal pain and no anesthesia required.
• The incidence of infectious complications following endometrial biopsy is presumed to be negligible, with limited available data.

Observation:

• A 52-year-old woman presented with septic shock and multiple organ failure.
• These severe complications occurred unusually after a Pipelle endometrial sampling procedure.
• Lower abdominal pain is a typical symptom of pelvic infection, but atypical presentations can occur.

Findings:

• The case report details an unexpected and severe infectious complication following a routine Pipelle endometrial biopsy.
• Septic shock and multiple organ failure represent a rare but critical adverse event associated with this common gynecological procedure.
• The patient's atypical presentation underscores the importance of considering infectious etiologies.

Implications:

• This case emphasizes that even seemingly minor procedures like Pipelle endometrial biopsy carry a risk of serious infectious complications.
• Clinicians should be vigilant for atypical symptoms, such as abdominal pain, after endometrial biopsy, as they may indicate a significant infection.
• Awareness of this rare complication is crucial for prompt diagnosis and management, potentially improving patient outcomes and safety protocols.