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Updated: Feb 7, 2026

An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur
Published on: October 23, 2017
Peculiarities of Osteogenesis by Periosteal Cells after Experimental Ectopic Transplantation
A A Ivanov1, T I Danilova2, O P Popova2
1I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow, Russia. aaivanov@1msmu.ru.
Abstract:
We carried out a comparative study of the features of osteogenesis from the progenitor osteogenic periosteal cells in rabbit and human. At the initial stages, high osteogenic potential of both human and rabbit periosteal cells was observed. However, at the later stages, the cell response favors resorption of the new bone tissue formed from periosteal cells in rabbits, but does not affect the bone tissue formed from human progenitor osteogenic periosteal cells. These functional characteristics of rabbit periosteal cells should be considered when planning the experiment.
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