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Updated: Feb 7, 2026

Synthesis and Characterization of Functionalized Metal-organic Frameworks
Published on: September 5, 2014
Parallel Approaches for the Functionalization of Thietes: α-Metalation versus C-H Activation
Michael Eisold1, Adrian Müller-Deku1, Felix Reiners1
1Department of Chemistry and Pharmacy , Ludwig-Maximilians-University , Butenandtstraße 5-13 , 81377 Munich , Germany.
Abstract:
For the first time, an approach to 3,4-disubstituted thietes was developed through two complementary paths. While the first one relies on α-metalation, the second is based on direct C-H functionalization. A new library of sophisticated sulfur-containing four-membered rings is described, paving the way to new bioactive analogues and small heterocycle incorporation.
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