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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
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Improving Long-Term Outcomes After Extracorporeal Membrane Oxygenation: From Observational Follow-Up Programs Toward
Hanneke IJsselstijn1,2, Maayke Hunfeld1, Raisa M Schiller1,2
1Division of Pediatric Intensive Care, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, Netherlands.
Frontiers in Pediatrics
|July 18, 2018
Summary
Extracorporeal membrane oxygenation (ECMO) survivors, especially neonates, require structured, long-term follow-up. This ensures comprehensive evaluation of neurological outcomes and overall health post-treatment.
Area of Science:
- Pediatric critical care medicine
- Neonatal intensive care
- Cardiorespiratory support
Background:
- Extracorporeal membrane oxygenation (ECMO) has improved survival rates for neonates and children with cardiorespiratory failure.
- The focus has shifted from mortality reduction to understanding and preventing long-term morbidities in survivors.
Purpose of the Study:
- To review changes in the ECMO population and treatment affecting long-term outcomes.
- To discuss diagnostic methods for evaluating neurological morbidities and their prognostic value.
- To recommend standardized, interdisciplinary follow-up protocols for ECMO survivors.
Main Methods:
- Review of existing literature and observational follow-up data from neonatal ECMO survivors.
- Analysis of factors influencing long-term outcomes, including population changes and treatment modalities.
- Evaluation of diagnostic tools for neurological assessment and prognostication.
Main Results:
- Most available long-term data originate from observational studies of neonatal ECMO survivors.
- Neurological morbidities are a significant concern requiring careful evaluation.
- Follow-up recommendations are contingent upon neurological status, disease severity, and ECMO indication.
Conclusions:
- Standardized, interdisciplinary long-term follow-up is crucial for ECMO survivors.
- Comprehensive evaluation across multiple domains is recommended.
- Structured follow-up facilitates outcome assessment and intervention effectiveness analysis.
Keywords:
extracorporeal membrane oxygenationfollow-uplong-term outcomesneurodevelopmentneuromonitoringMore Related Videos
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