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Interdelivery Interval and Medically Indicated Preterm Delivery
Annie M Dude1, William A Grobman1
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
American Journal of Perinatology
|July 18, 2018
Summary
Longer intervals between pregnancies increase the likelihood of medically indicated preterm birth. Shorter intervals were associated with fewer medically indicated preterm deliveries.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Medicine
- Reproductive Health
Background:
- Preterm birth remains a leading cause of neonatal morbidity and mortality.
- Understanding factors influencing preterm delivery subtypes is crucial for improving perinatal outcomes.
- The impact of interdelivery interval on the indication for preterm birth requires further investigation.
Purpose of the Study:
- To investigate the association between the length of the interdelivery interval and the likelihood of medically indicated preterm delivery.
- To compare characteristics of women experiencing medically indicated versus spontaneous preterm deliveries.
- To determine if longer interpregnancy intervals are linked to a higher incidence of medically indicated preterm births.
Main Methods:
- A case-control study was conducted involving women with two consecutive singleton live births at the same institution (2005-2015).
- Preterm deliveries were categorized as spontaneous or medically indicated based on delivery circumstances.
- Interdelivery intervals were grouped into <18 months, 18-59 months, and ≥60 months.
Main Results:
- A significant association was found between longer interdelivery intervals and a higher likelihood of medically indicated preterm delivery (37.4% for ≥60 months vs. 25.7% for 18-59 months).
- Women with shorter interdelivery intervals (<18 months) showed a lower likelihood of medically indicated preterm delivery (19.3%).
- This relationship remained significant after adjusting for potential confounding factors.
Conclusions:
- The findings suggest that a longer interdelivery interval is a risk factor for medically indicated preterm delivery.
- Obstetric providers should consider the interdelivery interval when assessing risks for preterm birth complications.
- Further research may explore the underlying mechanisms linking longer interpregnancy intervals to medically indicated preterm births.
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