Evaluation of transient respiratory motion artifact at gadoxetate disodium-enhanced MRI-Influence of different
Kristina I Ringe1, Christian von Falck1, Hans-Jürgen Raatschen1
1Hannover Medical School, Department of Diagnostic and Interventional Radiology, Hannover, Germany.
Purpose:
To evaluate transient severe respiratory motion artifacts (TSM) at gadoxetate disodium-enhanced MRI dependent on the mode of contrast agent application.
Methods:
200 patients (71f, 129m; mean 51y) were included in this retrospective IRB-approved study. Contrast application protocols (n = 4) differed with regards to injection rate (2ml or 1ml/sec), dose (weight-based or fixed 10ml) and supplemental oxygen administration (yes/no). SNR measurements were performed in the aorta and portal vein. Qualitatively, three readers assessed arterial phase image quality and TSM independently (4- and 5-point scale, respectively). Quantitative and qualitative results were compared (Kruskal-Wallis test, Dunn's multiple comparison test). The influence of different contrast agent application parameters on the occurrence of respiratory motion artifacts was assessed (univariate analysis). Interrater agreement and reliability were calculated (intraclass correlation coefficient, ICC)).
Results:
Use of a lower contrast injection rate resulted in significantly higher arterial SNR in the aorta and portal vein (p<0.05). TSM was observed in 12% of examinations. Neither injection rate, contrast dose, nor oxygen had a significant influence. Interrater agreement and reliability for evaluation of image quality and respiratory motion were substantial/ almost perfect (ICC = 0.640-0.915).
Conclusions:
Technical factors regarding the specific mode of contrast application do not seem to significantly reduce the incidence of severe transient respiratory motion artifacts.
Insights
This study found that altering contrast injection methods did not significantly reduce severe respiratory motion artifacts in MRI scans. Image quality and motion artifact assessment showed reliable results among readers.
Area of Science:
- Radiology
- Medical Imaging
- Diagnostic Imaging
Background:
- Transient severe respiratory motion (TSM) artifacts can degrade MRI quality.
- Gadoxetate disodium-enhanced MRI is widely used for liver imaging.
- Optimizing contrast administration is crucial for minimizing motion artifacts.
Purpose of the Study:
- To evaluate the impact of different gadoxetate disodium contrast agent application methods on TSM.
- To determine if varying injection rates, doses, or oxygen administration affects respiratory motion artifacts.
Main Methods:
- Retrospective analysis of 200 patients undergoing gadoxetate disodium-enhanced MRI.
- Four contrast application protocols varying injection rate, dose, and oxygen use were compared.
- Signal-to-noise ratio (SNR) was measured, and image quality/TSM were qualitatively assessed by three readers.
Main Results:
- Lower contrast injection rates led to significantly higher arterial SNR in the aorta and portal vein.
- TSM occurred in 12% of examinations, with no significant influence from injection rate, dose, or oxygen.
- Reader agreement for image quality and motion assessment was substantial to almost perfect (ICC = 0.640-0.915).
Conclusions:
- Technical factors related to contrast agent administration, including injection rate and dose, do not significantly reduce severe TSM in gadoxetate disodium-enhanced MRI.
- Further research may be needed to explore other strategies for artifact reduction.
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