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Updated: Feb 7, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Endovascular Therapy for Acute Ischemic Stroke: A Comprehensive Review of Current Status
İsmail D Kilic1, Abdul Hakeem2, Konstantinos Marmagkiolis3
1Pamukkale University Hospital, Department of Cardiology, Denizli, Turkey.
Insights
Endovascular therapy is now a key treatment for acute ischemic stroke caused by large vessel occlusion in the anterior circulation. This review covers its technical aspects and supporting evidence.
Area of Science:
- Neurology
- Interventional Radiology
- Vascular Medicine
Background:
- Stroke is a major global cause of death and disability.
- Current fibrinolytic therapy shows limitations in achieving vessel patency and improving functional outcomes.
- Advances in endovascular techniques have emerged for acute ischemic stroke.
Purpose of the Study:
- To review the current evidence and technical considerations for endovascular therapy in acute ischemic stroke.
- To highlight the established role of endovascular treatment for large vessel occlusions.
- To provide an overview of the management of acute stroke.
Main Methods:
- Review of recent randomized controlled trials on endovascular therapy for ischemic stroke.
- Analysis of technical aspects related to endovascular procedures.
- Synthesis of the current evidence base supporting endovascular interventions.
Main Results:
- Randomized trials have confirmed the efficacy of endovascular therapy.
- Endovascular treatment improves outcomes for large vessel occlusive strokes in the anterior circulation.
- Established role for endovascular therapy in specific stroke populations.
Conclusions:
- Endovascular therapy is a critical component in the management of acute ischemic stroke.
- The evidence supports its use for large vessel occlusions in the anterior circulation.
- Further understanding of technical nuances and ongoing research will refine treatment strategies.
Abstract:
Stroke remains among the leading causes of disability and death worldwide. Fibrinolytic therapy is associated with poor patency and functional outcomes. Recently, multiple randomized trials have been published that have consolidated the role of endovascular therapy for ischemic stroke due to large vessel occlusion in the anterior cerebral circulation. This manuscript reviews the current understanding of the endovascular management of acute stroke including technical aspects and current evidence base.
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