[EVALUATION OF THE EFFICACY OF THE EXTENDED-COMBINED OPERATIONS ON THE ZONES OF PRE- AND PARATRACHEAL METASTASIS IN...

After a retrospective study of the history of patients with a diagnosis of laryngeal cancer (2151 people), as well as the analysis of their own clinical materials, subglottic cancer was found in 103 patients, which was 4.8% of the total number of patients admitted to the hospital. One group of patients (n=39) underwent laryngectomy with subsequent irradiation, another group (n=64) was carried out by us developed and introduced into practice the method of the extended-combined laryngectomy. This method involves the mobilization and excision of the cervical tissue with lymph nodes located within it at the level VI level, the mobilization of the larynx and its removal at the level of the V-th or VI-th tracheal rings, as well as the dissection or thyroid share from the side of lesion in the unilateral localization, or complete dissection in the circular localization of the tumor. The comparative analysis was carried out on the frequency of metastasis in the pre- and paratracheal zones during the subglottic cancer of the larynx. A statistically significant (p<0.001) decrease in the incidence of metastases was observed in the advanced-combined laryngectomy (14.5%) compared with the traditional treatment (66.5%). If we consider that the main cause of death of patients with a tumor, both in subglottic cancer of the larynx and any other localization is metastasis, the development and introduction of new surgical methods that reduce the incidence of metastasis is a major breakthrough in practical oncology.