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Updated: Feb 7, 2026
09:26
Synthesis and Characterization of Supramolecular Colloids
Published on: April 22, 2016
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Compressible colloidal clusters from Pickering emulsions and their DNA functionalization.
In-Seong Jo1, Joon Suk Oh2, Shin-Hyun Kim3
1School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea. yigira@skku.edu.
Chemical Communications (Cambridge, England)
|July 25, 2018
Summary
Researchers created DNA-coated colloidal clusters from polymer particles. These clusters can be reshaped after formation, allowing for tunable compression, which is useful for advanced material design.
Area of Science:
- Polymer Science
- Materials Science
- Nanotechnology
Background:
- Colloidal clusters are building blocks for advanced materials.
- Controlling cluster shape and properties is crucial for their applications.
- Existing methods often lack flexibility in post-assembly modification.
Purpose of the Study:
- To develop a method for creating tunable colloidal clusters.
- To functionalize these clusters with DNA for specific interactions.
- To enable post-assembly shape modification of the clusters.
Main Methods:
- Assembling azide-functionalized polymer particles at oil-in-water emulsion droplet interfaces.
- Inducing cluster formation via slow oil evaporation.
- Coating the clusters with DNA using copper-free click chemistry (alkyne-azide cycloaddition).
- Utilizing the non-crosslinked nature of particles for plasticization and shape control.
Main Results:
- Successfully prepared azide-functionalized colloidal clusters.
- Achieved DNA coating on the clusters via SPAAC reaction.
- Demonstrated that the non-crosslinked nature allows for post-assembly shape modification.
- Showcased control over the cluster compression ratio through plasticization.
Conclusions:
- A novel method for creating DNA-coated colloidal clusters with tunable shapes was established.
- The non-crosslinked particle design enables post-assembly plasticization for controlled compression.
- These findings offer new possibilities for designing responsive and adaptable colloidal materials.
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