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Updated: Feb 7, 2026

Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
[Heterotopic ossification on a midline laparotomy scar after digestive surgery: etiopathogenic discussion about two
M Oukabli1, Ali A Ait2, M Fahsi2
1Service d'anatomie pathologique de l'Hôpital Militaire d'Instruction Mohamed V Rabat Maroc.
Abstract:
Heterotopic ossification (HO) is rarely seen after abdominal surgery and usually occurs after orthopedic surgery. It is a benign affection with an unknown mechanism and an unpredictable occurrence rate; but some etiopathogenic hypotheses have been put forward. Therapeutic attitudes were not assessed in this study. We report two observations of heterotopic ossification on mid-line laparotomy scar which could support the etiopathogenic hypothesis of osteoblastic cells migration in granulation tissue from the neighbouring bone tissue, particularly from the sternum or pubian structures. The etiopathogenic mechanism and treatment of this affection are discussed with regards to previously published literature.
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