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Uncommon presentation of chromoblastomycosis
Yashwant Tawade1, Aparna Gaikwad1, Avinash Deodhar1
1Department of Dermatology, KEM Hospital, Pune, Maharashtra, India.
Cutis
|August 1, 2018
Summary
Chromoblastomycosis is a challenging fungal infection. Amphotericin B proved effective for a patient unresponsive to standard treatments, offering a new therapeutic option.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Chromoblastomycosis is a rare subcutaneous fungal infection endemic to tropical and subtropical areas.
- It results from skin inoculation by dematiaceous fungi and presents a therapeutic challenge due to resistance.
- Current treatment lacks evidence-based protocols, with itraconazole and terbinafine as first-line options.
Observation:
- A 25-year-old dairy farmer presented with a 20-year history of verrucous lesions on both cheeks.
- The patient's condition was refractory to initial treatments.
Findings:
- This case report details the successful use of amphotericin B in treating a recalcitrant chromoblastomycosis case.
- Amphotericin B demonstrated efficacy in a patient who did not respond to first-choice antifungal drugs.
Implications:
- The findings suggest amphotericin B as a potential alternative treatment for difficult-to-treat chromoblastomycosis.
- This case expands therapeutic options for managing this uncommon mycosis.
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