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Related Experiment Video

Updated: Feb 7, 2026

Using Unfixed, Frozen Tissues to Study Natural Mucin Distribution

Using Unfixed, Frozen Tissues to Study Natural Mucin Distribution

Published on: September 21, 2012

Mucinous Nevus.

Min Young Lee¹, Ji Yeon Byun¹, Hae Young Choi¹

¹Department of Dermatology, Ewha Womans University College of Medicine, Seoul, Korea.

Annals of Dermatology

|August 2, 2018

Summary

This study reports a rare case of mucinous nevus, a skin condition characterized by mucin deposition. The findings highlight the importance of recognizing this uncommon entity in clinical practice.

Area of Science:

Dermatology
Histopathology

Background:

Mucinous nevus is an uncommon skin condition, classified as either cutaneous mucinosis or connective tissue nevus.
It typically presents as grouped papules and plaques in a unilateral or zosteriform pattern.

Observation:

A 34-year-old male presented with grouped, gray-brown papules and confluent plaques on his lower back, present since childhood.
The lesions followed a zosteriform distribution.

Findings:

Histological examination revealed a characteristic band-like deposition of mucin in the superficial dermis, specifically the papillary dermis.
The diagnosis of mucinous nevus was confirmed.

Implications:

This case adds to the limited literature on mucinous nevi, emphasizing its rarity.

Keywords:

Cutaneous Mucin Nevus

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Accurate diagnosis relies on characteristic clinical presentation and histopathological findings of dermal mucin deposition.