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Pediatric Antimicrobial Stewardship: State of the Art

Emily J Godbout1, Amy L Pakyz2, John Daniel Markley3

  • 1Department of Pediatrics, Division of Pediatric Infectious Diseases, Children's Hospital of Richmond at Virginia Commonwealth University Health System, Children's Pavilion, 1000 East Broad St, PO Box 23298-0163, Richmond, VA, USA. emily.godbout@vcuhealth.org.

Current Infectious Disease Reports
|August 3, 2018
PubMed

Insights

Pediatric antimicrobial stewardship programs (ASPs) are effective in US hospitals. This review highlights the need for more research on unique pediatric populations and outpatient settings to combat antimicrobial resistance.

Area of Science:

  • Infectious Diseases
  • Pediatric Healthcare
  • Public Health

Background:

  • Antimicrobial resistance (AR) is a growing threat driven by antimicrobial misuse and overuse.
  • Professional organizations advocate for hospital-based antimicrobial stewardship programs (ASPs) to reduce antimicrobial use, improve outcomes, and lower costs.

Purpose of the Study:

  • To systematically review the effectiveness of pediatric antimicrobial stewardship programs (ASPs) and strategies in US inpatient settings.
  • To identify current gaps and challenges for pediatric populations, including unique groups and ambulatory settings.

Main Methods:

  • Systematic literature review of pediatric antimicrobial stewardship programs (ASPs) and strategies.
  • Analysis of data on effectiveness in inpatient and ambulatory settings.

Main Results:

  • Limited data exists on the effectiveness of inpatient pediatric ASPs, especially for unique populations.
  • There is a significant lack of evidence regarding ASPs in ambulatory settings.
  • The review supports the use of pediatric ASPs to optimize antimicrobial therapy.

Conclusions:

  • Pediatric ASPs are crucial for optimizing antimicrobial therapy in inpatient and unique pediatric populations.
  • Further research is needed to address the paucity of evidence in ambulatory settings.
  • Active stewardship and monitoring antimicrobial consumption are critical for program success.
Abstract

Keywords:
Antimicrobial resistanceAntimicrobial stewardshipPediatric antimicrobial stewardshipPediatric antimicrobial stewardship programPediatrics

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