Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

565
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
565
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

804
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
804
Physiology of Emotion01:20

Physiology of Emotion

3.4K
The physiology of emotions is a multifaceted process involving the autonomic nervous system, brain structures, hormones, and neurotransmitters. This intricate interplay dictates how emotions manifest in the body and influence behavior.
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...
3.4K
Emotional Expression01:26

Emotional Expression

1.1K
Emotional expression encompasses how individuals convey their emotions through verbal communication and non-verbal cues. These non-verbal actions include facial expressions, body language, and physical gestures, such as frowning or smiling. Among these, facial expressions play a crucial role in emotional expression and are understood universally, indicating a biological basis for how humans communicate emotions.
Universal Facial Expressions
Psychologist Paul Ekman identified seven basic...
1.1K
Labeling Emotion01:20

Labeling Emotion

735
Emotional labeling is a cognitive process that involves identifying and naming one's emotions, such as anger, fear, happiness, or sadness. It allows individuals to recognize and express their internal emotional states, a critical aspect of emotional regulation and communication. Labeling emotions requires more than mere recognition; it also involves drawing upon memory and contextual cues to understand the current situation and apply a corresponding emotional label. For instance, feeling...
735
Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

19.6K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating the impact of serotonergic psychedelic drugs, MDMA and ketamine on social cognition in psychiatric disorders: A scoping review.

Psychopharmacology·2026
Same author

Deep brain stimulation of the nucleus accumbens for severe self-injurious behaviour in children: long-term outcomes from a first-in-human pilot trial.

Molecular psychiatry·2026
Same author

Digital Health Monitoring and Intervention Suite for Stress in Frontline Nurses: Prospective Cohort Trial.

JMIR formative research·2026
Same author

Effectiveness and safety of hyperbaric oxygen therapy for psychiatric disorders: A systematic review and meta-analysis.

Psychiatry and clinical neurosciences·2026
Same author

Closed-loop stimulation modulates attention shifting in children.

Nature neuroscience·2026
Same author

Brain-age defines a structural signature of outcomes after vagus nerve stimulation in children.

Brain stimulation·2026

Related Experiment Video

Updated: Feb 6, 2026

Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder
05:49

Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder

Published on: October 13, 2018

12.8K

Post-traumatic stress disorder and chronic hyperconnectivity in emotional processing.

Benjamin T Dunkley1, Simeon M Wong2, Rakesh Jetly3

  • 1Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada; Neurosciences & Mental Health Program, The Hospital for Sick Children Research Institute, Toronto, Canada; Department of Medical Imaging, University of Toronto, Toronto, Canada.

Neuroimage. Clinical
|August 11, 2018
PubMed
Summary

Post-traumatic stress disorder (PTSD) involves an overactive threat response to stimuli like angry faces. This heightened brain connectivity for threat processing in PTSD is stable over two years, consistent with persistent symptoms.

Keywords:
AmygdalaFunctional connectivityImplicit emotional face processingMagnetoencephalography (MEG)Military combat soldiersPost-traumatic stress disorderPrefrontal cortex

More Related Videos

A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila
10:15

A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila

Published on: July 4, 2017

8.7K
Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury
05:51

Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury

Published on: May 15, 2016

9.5K

Related Experiment Videos

Last Updated: Feb 6, 2026

Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder
05:49

Stress-Enhanced Fear Learning, a Robust Rodent Model of Post-Traumatic Stress Disorder

Published on: October 13, 2018

12.8K
A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila
10:15

A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila

Published on: July 4, 2017

8.7K
Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury
05:51

Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury

Published on: May 15, 2016

9.5K

Area of Science:

  • Neuroscience
  • Psychiatry
  • Trauma Studies

Background:

  • Post-traumatic stress disorder (PTSD) is linked to exaggerated responses to threat cues, especially aggressive facial expressions.
  • The long-term stability of this neurophysiological hyperactive threat response in PTSD remains largely undetermined.

Purpose of the Study:

  • To investigate the temporal stability of implicit emotional face processing in soldiers with and without PTSD.
  • To assess the reliability of neurophysiological markers of threat hyper-responsiveness over a two-year period.

Main Methods:

  • Magnetoencephalography (MEG) was used to measure brain oscillations and synchrony in response to happy and angry faces.
  • The study included soldiers with and without PTSD at two time-points, approximately two years apart.
  • A mixed-effects model analyzed changes in neurophysiological responses and PTSD symptom severity.

Main Results:

  • Soldiers with PTSD exhibited elevated oscillatory connectivity when processing angry faces compared to happy faces.
  • This maladaptive hypersynchrony in PTSD was observed in subcortical regions (thalamus), ventromedial prefrontal cortex, and other brain areas.
  • The observed hyperconnectivity pattern remained stable over the two-year follow-up period, mirroring stable PTSD symptomatology.

Conclusions:

  • The findings support the theory that hypervigilance in PTSD is driven by rapid, bottom-up processing of threat stimuli.
  • This threat processing engages a widespread, synchronized neural network, which is a stable characteristic of PTSD.
  • The study demonstrates the long-term stability of neurophysiological markers associated with PTSD threat processing.