Internal radiation dose estimation using multiple D-shuttle dosimeters for positron emission tomography (PET): A
Md Shahidul Islam1,2,3, Shoichi Watanuki4, Manabu Tashiro4
1Division of Radiation Protection and Safety Control, Cyclotron and Radioisotope Centre, Tohoku University, Sendai, 980-8578, Japan.
Medical Physics
|August 12, 2018
Summary
A new method uses surface dosimeters to estimate internal radiation dose during PET scans. This technique accurately measures radioactivity, enhancing patient safety in nuclear medicine.
Area of Science:
- Nuclear Medicine
- Medical Physics
- Radiation Dosimetry
Background:
- Internal radiation dosimetry is crucial for positron emission tomography (PET) safety and regulatory compliance.
- Current methods for internal dose estimation in PET can be complex and invasive.
Purpose of the Study:
- To develop and validate a novel technique for estimating internal radiation dose in PET studies.
- To utilize multiple D-shuttle dosimeters placed on the body surface for dose assessment.
Main Methods:
- A maximum-likelihood expectation-maximization (MLEM) algorithm was employed to estimate organ radioactivity using D-shuttle dosimeter measurements.
- Monte Carlo simulations using the PHITS code were performed to model dose response.
- A phantom study with an NEMA body phantom filled with 18F-FDG was conducted to validate the technique.
Main Results:
- The technique accurately estimated radioactivity concentrations in source organs, showing a strong correlation (R² = 0.992) with actual measurements.
- Estimated initial radioactivities closely matched actual values across various phantom compartments (torso cavity and spheres).
- Radioactivity was successfully estimated at 2-minute intervals over a 110-minute period.
Conclusions:
- The proposed D-shuttle dosimeter technique demonstrated successful internal radiation dose estimation in a phantom study.
- This method offers a promising approach for clinical PET studies, improving the safety and accuracy of internal dosimetry.
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