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Ice water test in multiple sclerosis: A pilot trial.

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The ice water test effectively identifies hidden detrusor overactivity in multiple sclerosis patients. A new nomogram aids in categorizing severity, improving bladder dysfunction assessment.

Keywords:
ice water testmultiple sclerosisneurogenic bladder dysfunctionnomogramoveractive bladder

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Area of Science:

  • Urology
  • Neurology

Background:

  • Detrusor overactivity is a common complication in neurogenic bladder dysfunction.
  • Accurate assessment is crucial for effective management.

Purpose of the Study:

  • To evaluate the diagnostic value of the ice water test in multiple sclerosis patients.
  • To introduce and assess a novel ice water test nomogram for severity grading.

Main Methods:

  • Retrospective analysis of 201 ice water tests in multiple sclerosis patients.
  • Correlation of test results with incontinence episodes and sexual activity.
  • Development and application of an ice water test nomogram.

Main Results:

  • A positive ice water test was observed in 37.3% of patients, with significantly higher prevalence in men.
  • The test identified detrusor overactivity missed by routine cystometry in 16.5% of cases.
  • The nomogram successfully correlated with incontinence severity and aided in illustrating treatment progress.

Conclusions:

  • The ice water test is a valuable tool for detecting occult detrusor overactivity in neurogenic bladder.
  • The ice water test nomogram provides a method for categorizing severity.
  • Further validation may establish the ice water test as an objective measure for bladder dysfunction.