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Updated: Feb 6, 2026

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
Published on: February 27, 2011
A pH-responsive nanoprobe for turn-on 19F-magnetic resonance imaging
Chang Guo1, Suying Xu, Anila Arshad
1State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China. lywang@mail.buct.edu.cn.
Abstract:
We successfully fabricated 19F magnetic resonance imaging (MRI) nanoprobes by partly replacing the 2-methylimidazolate of the metal organic framework (MOF) matrix ZIF-8, of which the strong 19F MRI signal displays an interesting pH dependence property, indicating its great potential as a 19F MRI contrast agent for stimuli-responsive imaging with high penetration depth and low background.
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