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Liquid Chromatography-Mass Spectrometry Education for Clinical Laboratory Scientists
Judith A Stone1, Robert L Fitzgerald2
1Toxicology/Mass Spectrometry Laboratory, University of California San Diego Health System, Center for Advanced Laboratory Medicine, Suite 150, Room 1314, 10300 Campus Point Drive, San Diego, CA 92121, USA.
Clinics in Laboratory Medicine
|August 18, 2018
Summary
This study outlines essential training competencies for laboratory professionals using quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS) in patient care. It addresses the evolving automation in LC-MS/MS and highlights remaining gaps in training resources.
Area of Science:
- Clinical Chemistry
- Analytical Chemistry
- Laboratory Medicine
Background:
- Quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS) is crucial for patient care diagnostics.
- The field is advancing with increased automation, potentially altering personnel skill requirements.
Purpose of the Study:
- To define the need for specific training competencies in diagnostic laboratory personnel.
- To stratify the complexity of these training requirements.
- To propose detailed competency lists for effective LC-MS/MS utilization.
Main Methods:
- Literature review and expert consensus on training needs for LC-MS/MS.
- Stratification of competencies based on technical complexity and automation levels.
- Development of detailed competency frameworks for personnel.
Main Results:
- Identified critical training gaps despite increasing automation in LC-MS/MS.
- Proposed comprehensive competency lists tailored to different roles and expertise levels.
- Highlighted the ongoing need for robust training and assessment resources.
Conclusions:
- Standardized training competencies are vital for ensuring accuracy and reliability in patient care using LC-MS/MS.
- Addressing identified gaps in training resources is necessary for workforce preparedness.
- Continuous evaluation of competencies is required as LC-MS/MS technology evolves.
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