Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Line, Surface, and Volume Integrals

Line, Surface, and Volume Integrals

A line integral for a vector field is defined as the integral of the dot product of a vector function with an infinitesimal displacement vector along a prescribed path. If the prescribed path is closed, the integrals reduce to a closed-line integral. The closed-contour integral of the vector field is referred to in terms of the circulation of the vector field around the closed path. A vector with zero circulation around every closed path is called a conservative field, while one with non-zero...

The Sense of Self: Reflected Self-Appraisal and Social Comparison

The Sense of Self: Reflected Self-Appraisal and Social Comparison

According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...

Guidelines for Writing Outcome

Guidelines for Writing Outcome

When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...

Guidelines for Nursing Documentation I

Guidelines for Nursing Documentation I

Quality documentation and reporting share essential characteristics that ensure they are practical and valuable resources for those who use them. These characteristics are:
Factual:
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.

Guidelines for Sketching a Curve

Guidelines for Sketching a Curve

Curve sketching is a systematic method for understanding the overall behavior of a function by analyzing its key mathematical features. A function defines a curve on the coordinate plane, where the horizontal axis represents the input variable and the vertical axis represents the output. The process begins by determining the domain, which specifies the set of input values for which the function is defined and establishes the horizontal extent of the graph.Intercepts with the horizontal and...

Guidelines for Nursing Documentation II

Guidelines for Nursing Documentation II

Effective documentation is an integral part of nursing practice. Here are some essential guidelines to follow when documenting patient care:
Timely documentation is crucial to ensure continuity of care for patients. Any delays in recording or reporting medical information can result in medical errors and even adverse patient outcomes. From medication administration to diagnostic test results, every detail must be accurately and promptly documented to provide the best possible care for patients.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Second-harmonic bichromatic dispersive wave comb generation in a dissipative Kerr temporal soliton Fabry-Perot.

Optics letters·2026

Same author

Heterogeneously integrated lithium tantalate-on-silicon nitride modulators for high-speed communications.

Nature communications·2026

Same author

Copper damascene process-based high-performance thin-film lithium tantalate modulators.

Nature communications·2026

Same author

Advancing liquid biopsy: whispering gallery mode laser detection of the HER2 cancer biomarker on extracellular vesicles.

Lab on a chip·2025

Same author

Optical arbitrary waveform generation (OAWG) using actively phase-stabilized spectral stitching.

Light, science & applications·2025

Same author

Photonic-electronic arbitrary-waveform generation using quadrature multiplexing and active optical-phase stabilization.

Nature communications·2025

Search research articles

Related Experiment Video

Updated: Feb 6, 2026

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

Surface sensing with integrated optical waveguides: a design guideline.

Johannes Milvich, Daria Kohler, Wolfgang Freude

|August 19, 2018

Summary

This study introduces a surface sensitivity metric for optimizing waveguide-based biochemical sensors. It provides design guidelines for silicon nitride and silicon-on-insulator platforms to maximize detection influence on the guided mode.

More Related Videos

Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy

Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy

Published on: May 12, 2020

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

Published on: January 7, 2019

Related Experiment Videos

Last Updated: Feb 6, 2026

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy

Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy

Published on: May 12, 2020

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

Published on: January 7, 2019

Area of Science:

Photonics and Sensor Technology
Biochemical Sensing
Materials Science

Background:

Waveguide-based sensors detect molecules via surface binding.
Optimizing sensitivity requires maximizing the surface layer's influence on the guided mode's effective refractive index.
Common material platforms include silicon nitride and silicon-on-insulator (SOI).

Purpose of the Study:

To define a surface sensitivity metric for quantifying the impact of surface binding on waveguide modes.
To systematically analyze and optimize various waveguide types (strip, slot, double slot, SWG) for enhanced sensitivity.
To provide universal design guidelines for selecting and optimizing waveguide platforms for biochemical sensing.

Main Methods:

Development of a surface sensitivity metric.
Systematic analysis and optimization of silicon nitride and SOI waveguides.
Comparison of different waveguide designs including simple strips, slot, double slot, and sub-wavelength gratings (SWG).

Main Results:

Quantification of surface sensitivity across different waveguide types and material platforms.
Identification of optimal waveguide designs for maximizing surface layer influence.
Establishment of universal design guidelines based on physical trends and limitations.

Conclusions:

The defined surface sensitivity metric enables effective comparison of waveguide platforms.
Optimized waveguide designs, particularly slot and SWG structures, offer superior sensitivity.
Findings facilitate the selection of appropriate waveguide platforms and optimization for specific biochemical sensing tasks.