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Updated: Dec 19, 2025

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
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Choroidal Melanoma Resection.

Hany S Hamza1, Abdelrahman M Elhusseiny1

  • 1Department of Ophthalmology, Kasr Al-Ainy Medical School, Cairo University, Giza, Egypt.

Middle East African Journal of Ophthalmology
|August 21, 2018
PubMed
Summary
This summary is machine-generated.

Surgical resection, including endoresection and exoresection, offers effective treatment options for choroidal melanoma. Combining surgery with radiotherapy can significantly reduce tumor recurrence rates.

Keywords:
Choroidal melanomaendoresectionexoresectiongamma kniferadiotherapy

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Area of Science:

  • Ophthalmology
  • Surgical Oncology

Background:

  • Uveal melanoma is the most common primary intraocular malignancy.
  • Choroidal melanoma is the most frequent site of uveal melanoma.
  • Treatment for choroidal melanoma has evolved from enucleation to diverse therapeutic modalities.

Purpose of the Study:

  • To review the indications and complications of various choroidal melanoma treatment techniques.
  • To focus on the surgical resection methods: endoresection and exoresection.
  • To analyze the role of adjuvant radiotherapy in surgical outcomes.

Main Methods:

  • Review of published data from indexed journals and books.
  • Analysis of treatment options including radiotherapy, laser photocoagulation, thermotherapy, and surgical resection.
  • Focus on transscleral (exoresection) and internal (endoresection) surgical approaches.

Main Results:

  • Radiotherapy is a primary treatment in many centers, often used adjunctively with surgery.
  • Preoperative stereotactic radiotherapy and postoperative brachytherapy can decrease recurrence.
  • Surgical resection (endoresection and exoresection) is a key therapeutic option.

Conclusions:

  • Surgical resection is a viable and important treatment for choroidal melanoma.
  • Combination therapy with radiotherapy enhances surgical success by reducing recurrence.
  • The choice of treatment depends on tumor characteristics and patient factors.