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Combining Two Selection Principles: Sensor Arrays Based on Both Biomimetic Recognition and Chemometrics.
Wim Cuypers1, Peter A Lieberzeit1
1Department of Physical Chemistry, Faculty for Chemistry, University of Vienna, Vienna, Austria.
Frontiers in Chemistry
|August 22, 2018
Summary
Electronic noses and tongues use biomimetic sensor arrays for enhanced selectivity. Combining chemical selectivity with data analysis improves analyte quantification and understanding of natural olfaction.
Area of Science:
- Biomimetic sensor technology
- Chemometrics and analytical chemistry
Background:
- Electronic noses (e-noses) and electronic tongues (e-tongues) mimic biological senses using sensor arrays for sample analysis.
- Current sensor arrays often lack high selectivity, relying on chemometric data treatment for pattern recognition.
- Increased selectivity is crucial for accurate analyte quantification.
Purpose of the Study:
- To review sensor arrays developed using biomimetic approaches to enhance chemical selectivity.
- To explore the integration of chemical recognition with data analysis for improved sensor performance.
Main Methods:
- Focus on sensor arrays employing biomimetic strategies, including molecularly imprinted polymers (MIPs).
- Discuss systems utilizing whole cells, proteins, peptides, and aptamers in multisensor configurations.
- Highlight the combination of chemoselectivity and chemometrics.
Main Results:
- Biomimetic approaches, particularly MIPs, significantly increase the selectivity of individual sensors in e-noses and e-tongues.
- Multisensor systems incorporating biological elements like cells, proteins, peptides, and aptamers offer diverse detection capabilities.
- The combined approach of chemoselectivity and chemometrics enhances the analytical quality of quantitative data.
Conclusions:
- Integrating chemical recognition (chemoselectivity) with data processing (chemometrics) boosts the accuracy of quantitative analysis in sensor arrays.
- This synergistic approach deepens our understanding of natural olfactory processes.
- Biomimetic sensor arrays represent a promising advancement in analytical instrumentation for complex sample characterization.
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