PERSISTENT PLACOID MACULOPATHY IN A PATIENT WITH HIGH MYOPIA.

Area of Science:

• Ophthalmology
• Retinal Diseases

Background:

• High myopia is a significant risk factor for various ocular pathologies.
• Persistent placoid maculopathy is a rare condition affecting the macula.

Observation:

• A 59-year-old male with high myopia presented with unilateral visual blur.
• Multimodal imaging revealed subretinal thickening and fluid, initially without clear leakage on fluorescein angiography.
• The patient experienced recurrent, bilateral episodes despite initial anti-vascular endothelial growth factor (anti-VEGF) treatment.

Findings:

• Diagnosis of persistent placoid maculopathy was confirmed through multimodal imaging and clinical response.
• The condition exhibited a relapsing-remitting course with bilateral involvement.
• Combination therapy with anti-VEGF injections and immunomodulating agents led to disease quiescence.

Implications:

• Early intervention with anti-VEGF therapy and immunosuppression is crucial for managing persistent placoid maculopathy.
• This approach can lead to disease control and vision preservation in high-myopia patients.
• Multimodal imaging is essential for accurate diagnosis and monitoring of this condition.